34 Publikationen
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11730
Pragmatic MDR: a metadata repository with bottom-up standardization of medical metadata through reuse
S. Hegselmann, M. Storck, S. Gessner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, C. Mertens, S. Riepenhausen, S. Baier, B. Stöcker, J. Henke, C.O. Schmidt, M. Dugas, BMC Medical Informatics and Decision Making 21 (2021).
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| PubMed | Europe PMC
S. Hegselmann, M. Storck, S. Gessner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, C. Mertens, S. Riepenhausen, S. Baier, B. Stöcker, J. Henke, C.O. Schmidt, M. Dugas, BMC Medical Informatics and Decision Making 21 (2021).
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11741
Pruritus Intensity Scales across Europe: a prospective validation study
M. Storck, S. Sandmann, P. Bruland, M.P. Pereira, S. Steinke, C. Riepe, I. Soto‐Rey, S. Garcovich, M. Augustin, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, M. Dugas, S. Ständer, C. Zeidler, Journal of the European Academy of Dermatology and Venereology 35 (2021) 1176–1185.
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| PubMed | Europe PMC
M. Storck, S. Sandmann, P. Bruland, M.P. Pereira, S. Steinke, C. Riepe, I. Soto‐Rey, S. Garcovich, M. Augustin, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, M. Dugas, S. Ständer, C. Zeidler, Journal of the European Academy of Dermatology and Venereology 35 (2021) 1176–1185.
2020 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11574
Criteria Suggestive of Psychological Components of Itch and Somatoform Itch: Study of a Large Sample of Patients with Chronic Pruritus
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 100 (2020) adv00075-7.
ELSA
| DOI
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 100 (2020) adv00075-7.
2019 | Zeitschriftenaufsatz | ELSA-ID: 11558
Electronic Image Documentation of Patient Reported Outcomes Using Mobile Technologies.
I. Soto-Rey, T. Hardt, L. Hollenberg, P. Bruland, S. Ständer, M. Dugas, M. Storck, Stud Health Technol Inform 264 (2019) 1779–1780.
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| PubMed | Europe PMC
I. Soto-Rey, T. Hardt, L. Hollenberg, P. Bruland, S. Ständer, M. Dugas, M. Storck, Stud Health Technol Inform 264 (2019) 1779–1780.
2019 | Zeitschriftenaufsatz | ELSA-ID: 11569
Scientific Challenge in eHealth: MAPPATHON, a Metadata Mapping Challenge.
A. Kock-Schoppenhauer, P. Bruland, D. Kadioglu, D. Brammen, H. Ulrich, K. Kulbe, P. Duhm-Harbeck, J. Ingenerf, Stud Health Technol Inform 264 (2019) 1516–1517.
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| PubMed | Europe PMC
A. Kock-Schoppenhauer, P. Bruland, D. Kadioglu, D. Brammen, H. Ulrich, K. Kulbe, P. Duhm-Harbeck, J. Ingenerf, Stud Health Technol Inform 264 (2019) 1516–1517.
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11735
Which patients with chronic pruritus are presented for psychological assessment by their dermatologists? Results from a consecutive sample
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, British Journal of Dermatology 181 (2019) 1329–1330.
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| PubMed | Europe PMC
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, British Journal of Dermatology 181 (2019) 1329–1330.
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11738
Chronic pruritus patients with psychiatric and psychosomatic comorbidity are highly burdened: a longitudinal study
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2019).
ELSA
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| PubMed | Europe PMC
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2019).
2018 | Zeitschriftenaufsatz | ELSA-ID: 11561
Standardising the Development of ODM Converters: The ODMToolBox.
I. Soto-Rey, P. Neuhaus, P. Bruland, S. Geßner, J. Varghese, S. Hegselmann, T. Brix, M. Dugas, M. Storck, Stud Health Technol Inform 247 (2018) 231–235.
ELSA
| PubMed | Europe PMC
I. Soto-Rey, P. Neuhaus, P. Bruland, S. Geßner, J. Varghese, S. Hegselmann, T. Brix, M. Dugas, M. Storck, Stud Health Technol Inform 247 (2018) 231–235.
2018 | Zeitschriftenaufsatz | ELSA-ID: 11577
Compatibility Between Metadata Standards: Import Pipeline of CDISC ODM to the Samply.MDR.
A. Kock-Schoppenhauer, H. Ulrich, S. Wagen-Zink, P. Duhm-Harbeck, J. Ingenerf, P. Neuhaus, M. Dugas, P. Bruland, Studies in Health Technology and Informatics 247 (2018) 221–225.
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| PubMed | Europe PMC
A. Kock-Schoppenhauer, H. Ulrich, S. Wagen-Zink, P. Duhm-Harbeck, J. Ingenerf, P. Neuhaus, M. Dugas, P. Bruland, Studies in Health Technology and Informatics 247 (2018) 221–225.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11582
Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial
S. Steinke, C. Zeidler, C. Riepe, P. Bruland, I. Soto-Rey, M. Storck, M. Augustin, S. Bobko, S. Garcovich, F.J. Legat, A. Lvov, L. Misery, N. Osada, A. Reich, E. Şavk, E. Serra-Baldrich, M. Streit, J.C. Szepietowski, W. Weger, M. Dugas, S. Ständer, Journal of the American Academy of Dermatology 79 (2018) 457-463.e5.
ELSA
| DOI
S. Steinke, C. Zeidler, C. Riepe, P. Bruland, I. Soto-Rey, M. Storck, M. Augustin, S. Bobko, S. Garcovich, F.J. Legat, A. Lvov, L. Misery, N. Osada, A. Reich, E. Şavk, E. Serra-Baldrich, M. Streit, J.C. Szepietowski, W. Weger, M. Dugas, S. Ständer, Journal of the American Academy of Dermatology 79 (2018) 457-463.e5.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11732
ODM Data Analysis—A tool for the automatic validation, monitoring and generation of generic descriptive statistics of patient data
T.J. Brix, P. Bruland, S. Sarfraz, J. Ernsting, P. Neuhaus, M. Storck, J. Doods, S. Ständer, M. Dugas, PLOS ONE 13 (2018).
ELSA
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| PubMed | Europe PMC
T.J. Brix, P. Bruland, S. Sarfraz, J. Ernsting, P. Neuhaus, M. Storck, J. Doods, S. Ständer, M. Dugas, PLOS ONE 13 (2018).
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11733
Connecting healthcare and clinical research: Workflow optimizations through seamless integration of EHR, pseudonymization services and EDC systems
P. Bruland, J. Doods, T. Brix, M. Dugas, M. Storck, International Journal of Medical Informatics 119 (2018) 103–108.
ELSA
| DOI
P. Bruland, J. Doods, T. Brix, M. Dugas, M. Storck, International Journal of Medical Informatics 119 (2018) 103–108.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11739
Cross‐European validation of the ItchyQoL in pruritic dermatoses
C. Zeidler, S. Steinke, C. Riepe, P. Bruland, I. Soto‐Rey, M. Storck, S. Garcovich, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, G. Yosipovitch, S.C. Chen, M. Dugas, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2018) 391–397.
ELSA
| DOI
C. Zeidler, S. Steinke, C. Riepe, P. Bruland, I. Soto‐Rey, M. Storck, S. Garcovich, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, G. Yosipovitch, S.C. Chen, M. Dugas, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2018) 391–397.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11740
Electronic Collection of Multilingual Patient-Reported Outcomes across Europe
I. Soto-Rey, M. Rehr, P. Bruland, C. Zeidler, C. Riepe, S. Steinke, S. Ständer, M. Dugas, M. Storck, Methods of Information in Medicine 57 (2018) e107–e114.
ELSA
| DOI
I. Soto-Rey, M. Rehr, P. Bruland, C. Zeidler, C. Riepe, S. Steinke, S. Ständer, M. Dugas, M. Storck, Methods of Information in Medicine 57 (2018) e107–e114.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11746
Comparison and transformation between CDISC ODM and EN13606 EHR standards in connecting EHR data with clinical trial research data
A. Tapuria, P. Bruland, B. Delaney, D. Kalra, V. Curcin, Digital Health 4 (2018).
ELSA
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| PubMed | Europe PMC
A. Tapuria, P. Bruland, B. Delaney, D. Kalra, V. Curcin, Digital Health 4 (2018).
2017 | Zeitschriftenaufsatz | ELSA-ID: 11560
The Portal of Medical Data Models: Where Have We Been and Where Are We Going?
S. Geßner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, I. Soto-Rey, M. Storck, J. Doods, M. Dugas, Stud Health Technol Inform 245 (2017) 858–862.
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| PubMed | Europe PMC
S. Geßner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, I. Soto-Rey, M. Storck, J. Doods, M. Dugas, Stud Health Technol Inform 245 (2017) 858–862.
2017 | Zeitschriftenaufsatz | ELSA-ID: 11576
What Information Does Your EHR Contain? Automatic Generation of a Clinical Metadata Warehouse (CMDW) to Support Identification and Data Access Within Distributed Clinical Research Networks.
P. Bruland, J. Doods, M. Storck, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 313–317.
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| PubMed | Europe PMC
P. Bruland, J. Doods, M. Storck, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 313–317.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11585
Chronic pruritus: evaluation of patient needs and treatment goals with a special regard to differences according to pruritus classification and sex
S. Steinke, P. Bruland, C.S. Blome, N. Osada, M. Dugas, F. Fritz, M. Augustin, S. Ständer, British Journal of Dermatology 176 (2017) 363–370.
ELSA
| DOI
S. Steinke, P. Bruland, C.S. Blome, N. Osada, M. Dugas, F. Fritz, M. Augustin, S. Ständer, British Journal of Dermatology 176 (2017) 363–370.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11587
S2O – A software tool for integrating research data from general purpose statistic software into electronic data capture systems
P. Bruland, M. Dugas, BMC Medical Informatics and Decision Making 17 (2017).
ELSA
| DOI
P. Bruland, M. Dugas, BMC Medical Informatics and Decision Making 17 (2017).
2017 | Zeitschriftenaufsatz | ELSA-ID: 11590
Integrating x4T-EDC into an Image-Portal to Establish an Ophthalmic Reading Center.
P. Bruland, U. Kathöfer, M. Treder, N. Eter, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 1254.
ELSA
| PubMed | Europe PMC
P. Bruland, U. Kathöfer, M. Treder, N. Eter, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 1254.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11734
Management of chronic pruritus: from the dermatological office to the specialized itch center: a review
M.P. Pereira, S. Steinke, P. Bruland, H.F. Ständer, M. Dugas, M. Augustin, S. Ständer, Itch 2 (2017) e6–e6.
ELSA
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| PubMed | Europe PMC
M.P. Pereira, S. Steinke, P. Bruland, H.F. Ständer, M. Dugas, M. Augustin, S. Ständer, Itch 2 (2017) e6–e6.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11743
European academy of dermatology and venereology European prurigo project: expert consensus on the definition, classification and terminology of chronic prurigo
M.P. Pereira, S. Steinke, C. Zeidler, C. Forner, C. Riepe, M. Augustin, S. Bobko, F. Dalgard, J. Elberling, S. Garcovich, U. Gieler, M. Gonçalo, J.A. Halvorsen, T.A. Leslie, M. Metz, A. Reich, E. Şavk, G. Schneider, E. Serra‐Baldrich, H.F. Ständer, M. Streit, J. Wallengren, K. Weller, A. Wollenberg, P. Bruland, I. Soto‐Rey, M. Storck, M. Dugas, E. Weisshaar, J.C. Szepietowski, F.J. Legat, S. Ständer, Journal of the European Academy of Dermatology and Venereology 32 (2017) 1059–1065.
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| PubMed | Europe PMC
M.P. Pereira, S. Steinke, C. Zeidler, C. Forner, C. Riepe, M. Augustin, S. Bobko, F. Dalgard, J. Elberling, S. Garcovich, U. Gieler, M. Gonçalo, J.A. Halvorsen, T.A. Leslie, M. Metz, A. Reich, E. Şavk, G. Schneider, E. Serra‐Baldrich, H.F. Ständer, M. Streit, J. Wallengren, K. Weller, A. Wollenberg, P. Bruland, I. Soto‐Rey, M. Storck, M. Dugas, E. Weisshaar, J.C. Szepietowski, F.J. Legat, S. Ständer, Journal of the European Academy of Dermatology and Venereology 32 (2017) 1059–1065.
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11566
Portal of medical data models: information infrastructure for medical research and healthcare
M. Dugas, P. Neuhaus, A. Meidt, J. Doods, M. Storck, P. Bruland, J. Varghese, Database 2016 (2016).
ELSA
| DOI
M. Dugas, P. Neuhaus, A. Meidt, J. Doods, M. Storck, P. Bruland, J. Varghese, Database 2016 (2016).
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11737
Baseline Characteristics and Prescription Patterns of Standard Drugs in Patients with Angiographically Determined Coronary Artery Disease and Renal Failure (CAD-REF Registry)
H. Reinecke, G. Breithardt, C. Engelbertz, R.E. Schmieder, M. Fobker, H.O. Pinnschmidt, B. Schmitz, P. Bruland, K. Wegscheider, H. Pavenstädt, E. Brand, PLOS ONE 11 (2016).
ELSA
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| PubMed | Europe PMC
H. Reinecke, G. Breithardt, C. Engelbertz, R.E. Schmieder, M. Fobker, H.O. Pinnschmidt, B. Schmitz, P. Bruland, K. Wegscheider, H. Pavenstädt, E. Brand, PLOS ONE 11 (2016).
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11744
Chronischer Pruritus
S. Ständer, H.F. Ständer, S. Steinke, P. Bruland, M. Dugas, M. Augustin, Der Hautarzt 67 (2016) 640–647.
ELSA
| DOI
| PubMed | Europe PMC
S. Ständer, H.F. Ständer, S. Steinke, P. Bruland, M. Dugas, M. Augustin, Der Hautarzt 67 (2016) 640–647.
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11745
Common data elements for secondary use of electronic health record data for clinical trial execution and serious adverse event reporting
P. Bruland, M. McGilchrist, E. Zapletal, D. Acosta, J. Proeve, S. Askin, T. Ganslandt, J. Doods, M. Dugas, BMC Medical Research Methodology 16 (2016).
ELSA
| DOI
P. Bruland, M. McGilchrist, E. Zapletal, D. Acosta, J. Proeve, S. Askin, T. Ganslandt, J. Doods, M. Dugas, BMC Medical Research Methodology 16 (2016).
2015 | Zeitschriftenaufsatz | ELSA-ID: 11572
Facing the challenges of chronic pruritus: a report from a multi-disciplinary medical itch centre in Germany.
S. Ständer, E. Pogatzki-Zahn, A. Stumpf, F. Fritz, B. Pfleiderer, A. Ritzkat, P. Bruland, T. Lotts, C. Müller-Tidow, G. Heuft, H.-J. Pavenstädt, G. Schneider, H. Van Aken, W. Heindel, H. Wiendl, M. Dugas, T.A. Luger, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 95 (2015) 266–271.
ELSA
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| PubMed | Europe PMC
S. Ständer, E. Pogatzki-Zahn, A. Stumpf, F. Fritz, B. Pfleiderer, A. Ritzkat, P. Bruland, T. Lotts, C. Müller-Tidow, G. Heuft, H.-J. Pavenstädt, G. Schneider, H. Van Aken, W. Heindel, H. Wiendl, M. Dugas, T.A. Luger, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 95 (2015) 266–271.
2015 | Zeitschriftenaufsatz | ELSA-ID: 11575
PIACS: A System for the Automatic Detection, Categorization and Comparison of Scratch-Related Skin Lesions in Dermatology.
P. Bruland, W. Hänse, F. Schedel, S. Ständer, F. Fritz, Studies in Health Technology and Informatics 216 (2015) 1042.
ELSA
| PubMed | Europe PMC
P. Bruland, W. Hänse, F. Schedel, S. Ständer, F. Fritz, Studies in Health Technology and Informatics 216 (2015) 1042.
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11583
Health-Related Quality of Life in Chronic Pruritus: An Analysis Related to Disease Etiology, Clinical Skin Conditions and Itch Intensity
B. Warlich, F. Fritz, N. Osada, P. Bruland, A. Stumpf, G. Schneider, M. Dugas, B. Pfleiderer, S. Ständer, Dermatology 231 (2015) 253–259.
ELSA
| DOI
B. Warlich, F. Fritz, N. Osada, P. Bruland, A. Stumpf, G. Schneider, M. Dugas, B. Pfleiderer, S. Ständer, Dermatology 231 (2015) 253–259.
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11584
European EADV network on assessment of severity and burden of Pruritus (PruNet): first meeting on outcome tools
S. Ständer, C. Zeidler, C. Riepe, S. Steinke, F. Fritz, P. Bruland, I. Soto‐Rey, M. Storck, T. Agner, M. Augustin, C. Blome, F. Dalgard, A.W.M. Evers, S. Garcovich, M. Gonçalo, J. Lambert, F.J. Legat, T. Leslie, L. Misery, U. Raap, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J. Szepietowski, J. Wallengren, E. Weisshaar, M. Dugas, Journal of the European Academy of Dermatology and Venereology 30 (2015) 1144–1147.
ELSA
| DOI
S. Ständer, C. Zeidler, C. Riepe, S. Steinke, F. Fritz, P. Bruland, I. Soto‐Rey, M. Storck, T. Agner, M. Augustin, C. Blome, F. Dalgard, A.W.M. Evers, S. Garcovich, M. Gonçalo, J. Lambert, F.J. Legat, T. Leslie, L. Misery, U. Raap, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J. Szepietowski, J. Wallengren, E. Weisshaar, M. Dugas, Journal of the European Academy of Dermatology and Venereology 30 (2015) 1144–1147.
2014 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11581
Relations between the characteristics and psychological comorbidities of chronic pruritus differ between men and women: women are more anxious than men
A. Stumpf, S. Ständer, B. Warlich, F. Fritz, P. Bruland, B. Pfleiderer, G. Heuft, G. Schneider, The British Journal of Dermatology : BJD 172 (2014) 1323–1328.
ELSA
| DOI
A. Stumpf, S. Ständer, B. Warlich, F. Fritz, P. Bruland, B. Pfleiderer, G. Heuft, G. Schneider, The British Journal of Dermatology : BJD 172 (2014) 1323–1328.
2012 | Zeitschriftenaufsatz | ELSA-ID: 11573
Interoperability in clinical research: from metadata registries to semantically annotated CDISC ODM.
P. Bruland, B. Breil, F. Fritz, M. Dugas, Studies in Health Technology and Informatics 180 (2012) 564–568.
ELSA
| PubMed | Europe PMC
P. Bruland, B. Breil, F. Fritz, M. Dugas, Studies in Health Technology and Informatics 180 (2012) 564–568.
2012 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11589
Multilingual Medical Data Models in ODM Format
J. Kenneweg, F. Fritz, P. Bruland, D. Doods, B. Trinczek, M. Dugas, B. Breil, Applied Clinical Informatics : ACI ; Official EJournal of IMIA and AMDIS 03 (2012) 276–289.
ELSA
| DOI
J. Kenneweg, F. Fritz, P. Bruland, D. Doods, B. Trinczek, M. Dugas, B. Breil, Applied Clinical Informatics : ACI ; Official EJournal of IMIA and AMDIS 03 (2012) 276–289.
2012 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11742
Erfassung von Pruritus – aktuelle Standards und Implikationen für die Praxis
S. Ständer, C. Blome, B. Breil, P. Bruland, U. Darsow, M. Dugas, A. Evers, F. Fritz, M. Metz, N.Q. Phan, U. Raap, A. Reich, G. Schneider, S. Steinke, J. Szepietowski, E. Weisshaar, M. Augustin, Der Hautarzt 63 (2012) 521–531.
ELSA
| DOI
| PubMed | Europe PMC
S. Ständer, C. Blome, B. Breil, P. Bruland, U. Darsow, M. Dugas, A. Evers, F. Fritz, M. Metz, N.Q. Phan, U. Raap, A. Reich, G. Schneider, S. Steinke, J. Szepietowski, E. Weisshaar, M. Augustin, Der Hautarzt 63 (2012) 521–531.
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34 Publikationen
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11730
Pragmatic MDR: a metadata repository with bottom-up standardization of medical metadata through reuse
S. Hegselmann, M. Storck, S. Gessner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, C. Mertens, S. Riepenhausen, S. Baier, B. Stöcker, J. Henke, C.O. Schmidt, M. Dugas, BMC Medical Informatics and Decision Making 21 (2021).
ELSA
| DOI
| PubMed | Europe PMC
S. Hegselmann, M. Storck, S. Gessner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, C. Mertens, S. Riepenhausen, S. Baier, B. Stöcker, J. Henke, C.O. Schmidt, M. Dugas, BMC Medical Informatics and Decision Making 21 (2021).
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11741
Pruritus Intensity Scales across Europe: a prospective validation study
M. Storck, S. Sandmann, P. Bruland, M.P. Pereira, S. Steinke, C. Riepe, I. Soto‐Rey, S. Garcovich, M. Augustin, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, M. Dugas, S. Ständer, C. Zeidler, Journal of the European Academy of Dermatology and Venereology 35 (2021) 1176–1185.
ELSA
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| PubMed | Europe PMC
M. Storck, S. Sandmann, P. Bruland, M.P. Pereira, S. Steinke, C. Riepe, I. Soto‐Rey, S. Garcovich, M. Augustin, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, M. Dugas, S. Ständer, C. Zeidler, Journal of the European Academy of Dermatology and Venereology 35 (2021) 1176–1185.
2020 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11574
Criteria Suggestive of Psychological Components of Itch and Somatoform Itch: Study of a Large Sample of Patients with Chronic Pruritus
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 100 (2020) adv00075-7.
ELSA
| DOI
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 100 (2020) adv00075-7.
2019 | Zeitschriftenaufsatz | ELSA-ID: 11558
Electronic Image Documentation of Patient Reported Outcomes Using Mobile Technologies.
I. Soto-Rey, T. Hardt, L. Hollenberg, P. Bruland, S. Ständer, M. Dugas, M. Storck, Stud Health Technol Inform 264 (2019) 1779–1780.
ELSA
| DOI
| PubMed | Europe PMC
I. Soto-Rey, T. Hardt, L. Hollenberg, P. Bruland, S. Ständer, M. Dugas, M. Storck, Stud Health Technol Inform 264 (2019) 1779–1780.
2019 | Zeitschriftenaufsatz | ELSA-ID: 11569
Scientific Challenge in eHealth: MAPPATHON, a Metadata Mapping Challenge.
A. Kock-Schoppenhauer, P. Bruland, D. Kadioglu, D. Brammen, H. Ulrich, K. Kulbe, P. Duhm-Harbeck, J. Ingenerf, Stud Health Technol Inform 264 (2019) 1516–1517.
ELSA
| DOI
| PubMed | Europe PMC
A. Kock-Schoppenhauer, P. Bruland, D. Kadioglu, D. Brammen, H. Ulrich, K. Kulbe, P. Duhm-Harbeck, J. Ingenerf, Stud Health Technol Inform 264 (2019) 1516–1517.
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11735
Which patients with chronic pruritus are presented for psychological assessment by their dermatologists? Results from a consecutive sample
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, British Journal of Dermatology 181 (2019) 1329–1330.
ELSA
| DOI
| PubMed | Europe PMC
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, British Journal of Dermatology 181 (2019) 1329–1330.
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11738
Chronic pruritus patients with psychiatric and psychosomatic comorbidity are highly burdened: a longitudinal study
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2019).
ELSA
| DOI
| PubMed | Europe PMC
G. Schneider, A. Grebe, P. Bruland, G. Heuft, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2019).
2018 | Zeitschriftenaufsatz | ELSA-ID: 11561
Standardising the Development of ODM Converters: The ODMToolBox.
I. Soto-Rey, P. Neuhaus, P. Bruland, S. Geßner, J. Varghese, S. Hegselmann, T. Brix, M. Dugas, M. Storck, Stud Health Technol Inform 247 (2018) 231–235.
ELSA
| PubMed | Europe PMC
I. Soto-Rey, P. Neuhaus, P. Bruland, S. Geßner, J. Varghese, S. Hegselmann, T. Brix, M. Dugas, M. Storck, Stud Health Technol Inform 247 (2018) 231–235.
2018 | Zeitschriftenaufsatz | ELSA-ID: 11577
Compatibility Between Metadata Standards: Import Pipeline of CDISC ODM to the Samply.MDR.
A. Kock-Schoppenhauer, H. Ulrich, S. Wagen-Zink, P. Duhm-Harbeck, J. Ingenerf, P. Neuhaus, M. Dugas, P. Bruland, Studies in Health Technology and Informatics 247 (2018) 221–225.
ELSA
| PubMed | Europe PMC
A. Kock-Schoppenhauer, H. Ulrich, S. Wagen-Zink, P. Duhm-Harbeck, J. Ingenerf, P. Neuhaus, M. Dugas, P. Bruland, Studies in Health Technology and Informatics 247 (2018) 221–225.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11582
Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial
S. Steinke, C. Zeidler, C. Riepe, P. Bruland, I. Soto-Rey, M. Storck, M. Augustin, S. Bobko, S. Garcovich, F.J. Legat, A. Lvov, L. Misery, N. Osada, A. Reich, E. Şavk, E. Serra-Baldrich, M. Streit, J.C. Szepietowski, W. Weger, M. Dugas, S. Ständer, Journal of the American Academy of Dermatology 79 (2018) 457-463.e5.
ELSA
| DOI
S. Steinke, C. Zeidler, C. Riepe, P. Bruland, I. Soto-Rey, M. Storck, M. Augustin, S. Bobko, S. Garcovich, F.J. Legat, A. Lvov, L. Misery, N. Osada, A. Reich, E. Şavk, E. Serra-Baldrich, M. Streit, J.C. Szepietowski, W. Weger, M. Dugas, S. Ständer, Journal of the American Academy of Dermatology 79 (2018) 457-463.e5.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11732
ODM Data Analysis—A tool for the automatic validation, monitoring and generation of generic descriptive statistics of patient data
T.J. Brix, P. Bruland, S. Sarfraz, J. Ernsting, P. Neuhaus, M. Storck, J. Doods, S. Ständer, M. Dugas, PLOS ONE 13 (2018).
ELSA
| DOI
| PubMed | Europe PMC
T.J. Brix, P. Bruland, S. Sarfraz, J. Ernsting, P. Neuhaus, M. Storck, J. Doods, S. Ständer, M. Dugas, PLOS ONE 13 (2018).
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11733
Connecting healthcare and clinical research: Workflow optimizations through seamless integration of EHR, pseudonymization services and EDC systems
P. Bruland, J. Doods, T. Brix, M. Dugas, M. Storck, International Journal of Medical Informatics 119 (2018) 103–108.
ELSA
| DOI
P. Bruland, J. Doods, T. Brix, M. Dugas, M. Storck, International Journal of Medical Informatics 119 (2018) 103–108.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11739
Cross‐European validation of the ItchyQoL in pruritic dermatoses
C. Zeidler, S. Steinke, C. Riepe, P. Bruland, I. Soto‐Rey, M. Storck, S. Garcovich, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, G. Yosipovitch, S.C. Chen, M. Dugas, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2018) 391–397.
ELSA
| DOI
C. Zeidler, S. Steinke, C. Riepe, P. Bruland, I. Soto‐Rey, M. Storck, S. Garcovich, C. Blome, S. Bobko, F.J. Legat, N. Potekaev, A. Lvov, L. Misery, W. Weger, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J.C. Szepietowski, G. Yosipovitch, S.C. Chen, M. Dugas, S. Ständer, Journal of the European Academy of Dermatology and Venereology 33 (2018) 391–397.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11740
Electronic Collection of Multilingual Patient-Reported Outcomes across Europe
I. Soto-Rey, M. Rehr, P. Bruland, C. Zeidler, C. Riepe, S. Steinke, S. Ständer, M. Dugas, M. Storck, Methods of Information in Medicine 57 (2018) e107–e114.
ELSA
| DOI
I. Soto-Rey, M. Rehr, P. Bruland, C. Zeidler, C. Riepe, S. Steinke, S. Ständer, M. Dugas, M. Storck, Methods of Information in Medicine 57 (2018) e107–e114.
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11746
Comparison and transformation between CDISC ODM and EN13606 EHR standards in connecting EHR data with clinical trial research data
A. Tapuria, P. Bruland, B. Delaney, D. Kalra, V. Curcin, Digital Health 4 (2018).
ELSA
| DOI
| PubMed | Europe PMC
A. Tapuria, P. Bruland, B. Delaney, D. Kalra, V. Curcin, Digital Health 4 (2018).
2017 | Zeitschriftenaufsatz | ELSA-ID: 11560
The Portal of Medical Data Models: Where Have We Been and Where Are We Going?
S. Geßner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, I. Soto-Rey, M. Storck, J. Doods, M. Dugas, Stud Health Technol Inform 245 (2017) 858–862.
ELSA
| PubMed | Europe PMC
S. Geßner, P. Neuhaus, J. Varghese, P. Bruland, A. Meidt, I. Soto-Rey, M. Storck, J. Doods, M. Dugas, Stud Health Technol Inform 245 (2017) 858–862.
2017 | Zeitschriftenaufsatz | ELSA-ID: 11576
What Information Does Your EHR Contain? Automatic Generation of a Clinical Metadata Warehouse (CMDW) to Support Identification and Data Access Within Distributed Clinical Research Networks.
P. Bruland, J. Doods, M. Storck, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 313–317.
ELSA
| PubMed | Europe PMC
P. Bruland, J. Doods, M. Storck, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 313–317.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11585
Chronic pruritus: evaluation of patient needs and treatment goals with a special regard to differences according to pruritus classification and sex
S. Steinke, P. Bruland, C.S. Blome, N. Osada, M. Dugas, F. Fritz, M. Augustin, S. Ständer, British Journal of Dermatology 176 (2017) 363–370.
ELSA
| DOI
S. Steinke, P. Bruland, C.S. Blome, N. Osada, M. Dugas, F. Fritz, M. Augustin, S. Ständer, British Journal of Dermatology 176 (2017) 363–370.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11587
S2O – A software tool for integrating research data from general purpose statistic software into electronic data capture systems
P. Bruland, M. Dugas, BMC Medical Informatics and Decision Making 17 (2017).
ELSA
| DOI
P. Bruland, M. Dugas, BMC Medical Informatics and Decision Making 17 (2017).
2017 | Zeitschriftenaufsatz | ELSA-ID: 11590
Integrating x4T-EDC into an Image-Portal to Establish an Ophthalmic Reading Center.
P. Bruland, U. Kathöfer, M. Treder, N. Eter, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 1254.
ELSA
| PubMed | Europe PMC
P. Bruland, U. Kathöfer, M. Treder, N. Eter, M. Dugas, Studies in Health Technology and Informatics 245 (2017) 1254.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11734
Management of chronic pruritus: from the dermatological office to the specialized itch center: a review
M.P. Pereira, S. Steinke, P. Bruland, H.F. Ständer, M. Dugas, M. Augustin, S. Ständer, Itch 2 (2017) e6–e6.
ELSA
| DOI
| PubMed | Europe PMC
M.P. Pereira, S. Steinke, P. Bruland, H.F. Ständer, M. Dugas, M. Augustin, S. Ständer, Itch 2 (2017) e6–e6.
2017 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11743
European academy of dermatology and venereology European prurigo project: expert consensus on the definition, classification and terminology of chronic prurigo
M.P. Pereira, S. Steinke, C. Zeidler, C. Forner, C. Riepe, M. Augustin, S. Bobko, F. Dalgard, J. Elberling, S. Garcovich, U. Gieler, M. Gonçalo, J.A. Halvorsen, T.A. Leslie, M. Metz, A. Reich, E. Şavk, G. Schneider, E. Serra‐Baldrich, H.F. Ständer, M. Streit, J. Wallengren, K. Weller, A. Wollenberg, P. Bruland, I. Soto‐Rey, M. Storck, M. Dugas, E. Weisshaar, J.C. Szepietowski, F.J. Legat, S. Ständer, Journal of the European Academy of Dermatology and Venereology 32 (2017) 1059–1065.
ELSA
| DOI
| PubMed | Europe PMC
M.P. Pereira, S. Steinke, C. Zeidler, C. Forner, C. Riepe, M. Augustin, S. Bobko, F. Dalgard, J. Elberling, S. Garcovich, U. Gieler, M. Gonçalo, J.A. Halvorsen, T.A. Leslie, M. Metz, A. Reich, E. Şavk, G. Schneider, E. Serra‐Baldrich, H.F. Ständer, M. Streit, J. Wallengren, K. Weller, A. Wollenberg, P. Bruland, I. Soto‐Rey, M. Storck, M. Dugas, E. Weisshaar, J.C. Szepietowski, F.J. Legat, S. Ständer, Journal of the European Academy of Dermatology and Venereology 32 (2017) 1059–1065.
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11566
Portal of medical data models: information infrastructure for medical research and healthcare
M. Dugas, P. Neuhaus, A. Meidt, J. Doods, M. Storck, P. Bruland, J. Varghese, Database 2016 (2016).
ELSA
| DOI
M. Dugas, P. Neuhaus, A. Meidt, J. Doods, M. Storck, P. Bruland, J. Varghese, Database 2016 (2016).
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11737
Baseline Characteristics and Prescription Patterns of Standard Drugs in Patients with Angiographically Determined Coronary Artery Disease and Renal Failure (CAD-REF Registry)
H. Reinecke, G. Breithardt, C. Engelbertz, R.E. Schmieder, M. Fobker, H.O. Pinnschmidt, B. Schmitz, P. Bruland, K. Wegscheider, H. Pavenstädt, E. Brand, PLOS ONE 11 (2016).
ELSA
| DOI
| PubMed | Europe PMC
H. Reinecke, G. Breithardt, C. Engelbertz, R.E. Schmieder, M. Fobker, H.O. Pinnschmidt, B. Schmitz, P. Bruland, K. Wegscheider, H. Pavenstädt, E. Brand, PLOS ONE 11 (2016).
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11744
Chronischer Pruritus
S. Ständer, H.F. Ständer, S. Steinke, P. Bruland, M. Dugas, M. Augustin, Der Hautarzt 67 (2016) 640–647.
ELSA
| DOI
| PubMed | Europe PMC
S. Ständer, H.F. Ständer, S. Steinke, P. Bruland, M. Dugas, M. Augustin, Der Hautarzt 67 (2016) 640–647.
2016 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11745
Common data elements for secondary use of electronic health record data for clinical trial execution and serious adverse event reporting
P. Bruland, M. McGilchrist, E. Zapletal, D. Acosta, J. Proeve, S. Askin, T. Ganslandt, J. Doods, M. Dugas, BMC Medical Research Methodology 16 (2016).
ELSA
| DOI
P. Bruland, M. McGilchrist, E. Zapletal, D. Acosta, J. Proeve, S. Askin, T. Ganslandt, J. Doods, M. Dugas, BMC Medical Research Methodology 16 (2016).
2015 | Zeitschriftenaufsatz | ELSA-ID: 11572
Facing the challenges of chronic pruritus: a report from a multi-disciplinary medical itch centre in Germany.
S. Ständer, E. Pogatzki-Zahn, A. Stumpf, F. Fritz, B. Pfleiderer, A. Ritzkat, P. Bruland, T. Lotts, C. Müller-Tidow, G. Heuft, H.-J. Pavenstädt, G. Schneider, H. Van Aken, W. Heindel, H. Wiendl, M. Dugas, T.A. Luger, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 95 (2015) 266–271.
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| DOI
| PubMed | Europe PMC
S. Ständer, E. Pogatzki-Zahn, A. Stumpf, F. Fritz, B. Pfleiderer, A. Ritzkat, P. Bruland, T. Lotts, C. Müller-Tidow, G. Heuft, H.-J. Pavenstädt, G. Schneider, H. Van Aken, W. Heindel, H. Wiendl, M. Dugas, T.A. Luger, Acta Dermato-Venereologica : A Journal for Clinical and Experimental Research in the Field of Dermatology and Venereology 95 (2015) 266–271.
2015 | Zeitschriftenaufsatz | ELSA-ID: 11575
PIACS: A System for the Automatic Detection, Categorization and Comparison of Scratch-Related Skin Lesions in Dermatology.
P. Bruland, W. Hänse, F. Schedel, S. Ständer, F. Fritz, Studies in Health Technology and Informatics 216 (2015) 1042.
ELSA
| PubMed | Europe PMC
P. Bruland, W. Hänse, F. Schedel, S. Ständer, F. Fritz, Studies in Health Technology and Informatics 216 (2015) 1042.
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11583
Health-Related Quality of Life in Chronic Pruritus: An Analysis Related to Disease Etiology, Clinical Skin Conditions and Itch Intensity
B. Warlich, F. Fritz, N. Osada, P. Bruland, A. Stumpf, G. Schneider, M. Dugas, B. Pfleiderer, S. Ständer, Dermatology 231 (2015) 253–259.
ELSA
| DOI
B. Warlich, F. Fritz, N. Osada, P. Bruland, A. Stumpf, G. Schneider, M. Dugas, B. Pfleiderer, S. Ständer, Dermatology 231 (2015) 253–259.
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11584
European EADV network on assessment of severity and burden of Pruritus (PruNet): first meeting on outcome tools
S. Ständer, C. Zeidler, C. Riepe, S. Steinke, F. Fritz, P. Bruland, I. Soto‐Rey, M. Storck, T. Agner, M. Augustin, C. Blome, F. Dalgard, A.W.M. Evers, S. Garcovich, M. Gonçalo, J. Lambert, F.J. Legat, T. Leslie, L. Misery, U. Raap, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J. Szepietowski, J. Wallengren, E. Weisshaar, M. Dugas, Journal of the European Academy of Dermatology and Venereology 30 (2015) 1144–1147.
ELSA
| DOI
S. Ständer, C. Zeidler, C. Riepe, S. Steinke, F. Fritz, P. Bruland, I. Soto‐Rey, M. Storck, T. Agner, M. Augustin, C. Blome, F. Dalgard, A.W.M. Evers, S. Garcovich, M. Gonçalo, J. Lambert, F.J. Legat, T. Leslie, L. Misery, U. Raap, A. Reich, E. Şavk, M. Streit, E. Serra‐Baldrich, J. Szepietowski, J. Wallengren, E. Weisshaar, M. Dugas, Journal of the European Academy of Dermatology and Venereology 30 (2015) 1144–1147.
2014 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11581
Relations between the characteristics and psychological comorbidities of chronic pruritus differ between men and women: women are more anxious than men
A. Stumpf, S. Ständer, B. Warlich, F. Fritz, P. Bruland, B. Pfleiderer, G. Heuft, G. Schneider, The British Journal of Dermatology : BJD 172 (2014) 1323–1328.
ELSA
| DOI
A. Stumpf, S. Ständer, B. Warlich, F. Fritz, P. Bruland, B. Pfleiderer, G. Heuft, G. Schneider, The British Journal of Dermatology : BJD 172 (2014) 1323–1328.
2012 | Zeitschriftenaufsatz | ELSA-ID: 11573
Interoperability in clinical research: from metadata registries to semantically annotated CDISC ODM.
P. Bruland, B. Breil, F. Fritz, M. Dugas, Studies in Health Technology and Informatics 180 (2012) 564–568.
ELSA
| PubMed | Europe PMC
P. Bruland, B. Breil, F. Fritz, M. Dugas, Studies in Health Technology and Informatics 180 (2012) 564–568.
2012 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11589
Multilingual Medical Data Models in ODM Format
J. Kenneweg, F. Fritz, P. Bruland, D. Doods, B. Trinczek, M. Dugas, B. Breil, Applied Clinical Informatics : ACI ; Official EJournal of IMIA and AMDIS 03 (2012) 276–289.
ELSA
| DOI
J. Kenneweg, F. Fritz, P. Bruland, D. Doods, B. Trinczek, M. Dugas, B. Breil, Applied Clinical Informatics : ACI ; Official EJournal of IMIA and AMDIS 03 (2012) 276–289.
2012 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11742
Erfassung von Pruritus – aktuelle Standards und Implikationen für die Praxis
S. Ständer, C. Blome, B. Breil, P. Bruland, U. Darsow, M. Dugas, A. Evers, F. Fritz, M. Metz, N.Q. Phan, U. Raap, A. Reich, G. Schneider, S. Steinke, J. Szepietowski, E. Weisshaar, M. Augustin, Der Hautarzt 63 (2012) 521–531.
ELSA
| DOI
| PubMed | Europe PMC
S. Ständer, C. Blome, B. Breil, P. Bruland, U. Darsow, M. Dugas, A. Evers, F. Fritz, M. Metz, N.Q. Phan, U. Raap, A. Reich, G. Schneider, S. Steinke, J. Szepietowski, E. Weisshaar, M. Augustin, Der Hautarzt 63 (2012) 521–531.